Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

 
Session Overview
Session
MS126, part 2: Euclidean distance geometry and its applications
Time:
Friday, 12/Jul/2019:
10:00am - 12:00pm

Location: Unitobler, F011
30 seats, 59m^2

Presentations
10:00am - 12:00pm

Euclidean distance geometry and its applications

Chair(s): Kaie Kubjas (Sorbonne Université)

Given a natural number d and a weighted graph G=(V,E), the fundamental problem in Euclidean distance geometry is to determine whether there exists a realization of the graph G in Rd such that distances between pairs of points are equal to the corresponding edge weights. This problem naturally arises in many applications that require recovering locations of objects from the distances between these objects. Usually, measurements of the distances are noisy and there can be missing data. Examples of applications are sensor network localization, molecular conformation, genome reconstruction, robotics and data visualization. Algebraic varieties and semialgebraic sets naturally come up in Euclidean distance geometry, since distances between objects are given by polynomials. Hence questions about uniqueness and finiteness of realizations are often algebraic in nature, whereas realizations are found using semidefinite or nonconvex optimization methods. The goal of this minisymposium is to present theory and applications of Euclidean distance geometry, and connect researchers working in Euclidean distance geometry with applied algebraic geometers.

 

(25 minutes for each presentation, including questions, followed by a 5-minute break; in case of x<4 talks, the first x slots are used unless indicated otherwise)

 

Rigidity theory and algebraic matroids

Jessica Sidman
Mount Holyoke College, USA

Consider a framework consisting of fixed length bars attached at flexible joints. The central question in rigidity theory is to determine if the resulting framework is rigid or flexible. The minimally locally rigid graphs in dimension d are the bases of a matroid which can be realized as a linear matroid in joint coordinates associated to the classical "rigidity matrix" or as the algebraic matroid in (squared) distance coordinates associated to the Cayley-Menger variety. In this talk we focus on what the algebraic matroid can tell us about stresses and finite motions. This is joint work with Zvi Rosen, Louis Theran, and Cynthia Vinzant.

 

Periodic framework enhancements

Ileana Streinu
Smith College, USA

A (periodic) bar-and-joint framework is a geometric (periodic) graph whose vertices are mapped to points in R^d (for a fixed dimension d) and its edges to straight-line segments between them. The framework’s configuration space consists in all the placements of the same graph which retain the edge lengths (and the abstract periodicity). We enhance the (periodic) bar-and-joint framework structure to include faces of higher dimensions and study several scenarios that preserve or alter in a controlled manner the dimension of the original configuration space.

 

Barvinok's Naive Algorithm in Distance Geometry

Leo Liberti1, Ky Vu2
1CNRS and Ecole Polytechnique, France, 2Chinese University of Hong Kong, P.R. China

In 1997, A. Barvinok gave a probabilistic algorithm to derive a feasible solution of a quadratically (equation) constrained problem from its semidefinite relaxation. We generalize this algorithm to handle matrix (instead of vector) variables and to two-sided inequalities, and derive a heuristic for the distance geometry problem. We showcase its computational performance on a set of instances related to protein conformation.

 

Mathematics of 3D genome reconstruction in diploid organisms

Kaie Kubjas
Sorbonne Université, France

The 3D organization of the genome plays an important role for gene regulation. Chromosome conformation capture techniques allow one to measure the number of contacts between genomic loci that are nearby in the 3D space. In this talk, we study the problem of reconstructing the 3D organization of the genome from whole genome contact frequencies in diploid organisms, i.e. organisms that contain two indistinguishable copies of each genomic locus. In particular, we study the identifiability of the 3D organization of the genome and optimization methods for reconstructing it. This talk is based on joint work with Anastasiya Belyaeva, Lawrence Sun and Caroline Uhler.